From 2008 to 2013, Cranston starred in the AMC series Breaking Bad, created by Vince Gilligan, in which he played Walter White, a high school chemistry teacher who is diagnosed with terminal lung cancer.
Walter teams up with former student Jesse Pinkman (played by Aaron Paul), to manufacture and sell methamphetamine to ensure the well-being of Walter's family after he dies.
That same year he made his second appearance for a recurring role on the CBS sitcom The King of Queens, playing Doug Heffernan's neighbor, Tim Sacksky. His theatrical credits include starring roles in The God of Hell, Chapter Two, The Taming of the Shrew, A Doll's House, Barefoot in the Park, Eastern Standard, Wrestlers and The Steven Weed Show, for which he won a Drama-Logue Award.
In 1998, he appeared in Steven Spielberg's Saving Private Ryan, as War Department Colonel I. In 2000, Cranston landed a leading role as Hal on the comedy series Malcolm in the Middle.
Cranston and Bill Cosby are the only actors to have won the award three consecutive times.He appeared as the more successful business colleague of Greg Kinnear's character in the film Little Miss Sunshine (2006).In September 2008, Cranston narrated a pre-teen adventure/fantasy audiobook called Adventures with Kazmir the Flying Camel.Cranston was also nominated three times for the Outstanding Supporting Actor in a Comedy Series for his role in Malcolm in the Middle.His role in Breaking Bad also earned him five Golden Globe nominations and one win in 2014, nine Screen Actors Guild Awards nominations with four wins, and six Satellite Awards nominations with four wins.